StorageSecure storage
Clean Cells, a GMP-licensed pharmaceutical company, benefits from more than 20 years of storage experience which includes dozens of projects with sponsors for short, middle, and long-term preservation of reagents, starting material and biological material of cellular and viral origins.
Our company is a leader in cell eukaryotic and virus banking and GMP-compliant quality control testing, two activities that have spontaneously led us to developing storage capacities within secure and monitored laboratories and in GMP and non-GMP environments.
Our facilities accommodate various biological substances, graded BSL-1 to BSL-3 (for “Biosafety Level”), GMO (Genetically Modified Organisms) and has experience handling very sensitive material.
Our specifications
Our metrology group performs full qualification of equipment prior to storing a variety of biological products. Various options are made available to sponsors.
Storage of eukaryotic material : liquid nitrogen (LN2) and freezer (<-150°C)
Preservation of eukaryotic cells requires exceptionally low temperatures (below -145°C) reached with ultra-low temperature freezers or tanks supplied with liquid nitrogen (or in liquid or vapor phases).
Our LN2 storage specifications and options include:
- Pharmaceutical grade nitrogen (liquid or vapor-phase);
- Tank: dedicated or shared (with individualized cryoboxes);
- Temperature monitoring : automatic;
- LN2 level monitoring: manual or automatic;
- Moniroting : 24/7
- LN2 filling: manual ou semi-automatic;
- Back-up system
Our ultra-low freezer-based storage offer includes the following characteristics:
- Storage of large and unconventional containers
- Continuous temperature monitoring
- Back-up generator
- Monitoring : 24/7
Storage of viral and prokaryotic material : -80°C freezers
Virus and procaryotic cells do not require temperatures as low as those required for eukaryotic cells. They are thus stored in freezers reaching -80°C with the following environment specifications and options:
- Storage: shared (individualized cryoboxes) with on-demand shelf reservation
- Continuous temperature monitoring
- Monitoring: 24/7
- Back-up system (freezer and generator)
Storage of reagents: -20°C and +4°C
Precious reagents, reagents with a short shelf-life or used in production in our laboratories can be subject to specific storage within -20°C or +4°C areas.
GMP environment
Clean Cells provides a “Good Manufacturing Practice” (GMP) environment which ensures high safety for biological and non-biological material stored with our facilities and increased traceability. Specifications include:
- Increased qualification and monitoring of storage, secure containment
- Continuous LN2 control (upon request)
- Enhanced documentation management
- Reporting (upon request)
- Safety optimization via segregation of samples into two freezers or two tanks
- Increased quality control testing on incoming biological material
- Reinforced management of shipment
- Carrier: selection and qualification
- Addition of probes